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ALLERGIC CASCADE (ALC)
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The prevalence of allergy has continued to increase in the US and other westernized countries. Statistics indicate that food allergy alone in the US is as high as 19%. A recent study of insurance claims in the US for peanut allergy alone indicates an annual rise in this allergy from 1.7% to 5.2% in children aged 1 year between 2011 and 2017. READ MORE...
KIT CONTENTS
Allergic Rhinitis
Alpha-gal
Allergen related to meat allergy said to be caused by tick bites; also called galactose-α-1,3-galactose
Atopic Dermatitis
Asthma
Basophils
Cytokine Storm
Dendritic Cells (DC)
Dendritic cells (DCs) are a key part of the immune system and play a central role in allergic responses. DCs are antigen-presenting cells that capture and process allergens, then present them to T cells to initiate an immune response. https://www.jacionline.org/article/S0091-6749(12)00355-7/fulltext
Eczema
Epinephrine
Eosinophils
Histamine
Histamine Receptors H1,2,3
Histamine Receptor H4
IgE
IgE Receptor, FcεR1
IgE-Producing Plasma Cells
Plasma cells develop from B lymphocytes (B cells), a type of white blood cell that is made in the bone marrow. Normally, when bacteria or viruses enter the body, some of the B cells will change into plasma cells. The plasma cells make antibodies to fight bacteria and viruses, to stop infection and disease.
IgG1
IgG4
Langerhans cells
Mast cell
MBC2s, Type 2-Polarized Memory B Cells
“Memory B cells (MBCs) contribute to circulating IgE by regenerating IgE-producing plasma cells upon allergen encounter. Here, we report a population of type 2-polarized MBCs defined as CD23hi, IL-4Rαhi, and CD32low at both the transcriptional and surface protein levels. These MBC2s are enriched in IgG1- and IgG4-expressing cells while constitutively expressing germline transcripts for IgE.” https://pubmed.ncbi.nlm.nih.gov/38324637/
MBC2 CD23hi Type 2-Polarizing Memory B Cells,
MBC2 IL-4Rαhi Type 2-Polarizing Memory B Cells,
MBC2 CD32low Type 2-Polarizing Memory B Cells,
Naïve CD4+ T Cells
“Via the uptake and presentation of allergens by dendritic cells residing in the respective mucosal tissue, naïve CD4+ T cells are activated and differentiate into Type 2 helper T cell (Th2) cells. Consecutively, Th2 cells and their cytokine production driven by IL-4 and IL-13 promote/facilitate the production of allergen-specific immunoglobulin E (IgE)antibodies from B cells.” https://pmc.ncbi.nlm.nih.gov/articles/PMC5535981/
TH1 / T Helper 1 Cell Response
“…T helper (Th) cells provide helper functions to other cells of the immune system—especially the antigen-presenting cells (APCs) such as macrophages, dendritic cells, and B cells—and are important for their activation and maturation. There are distinct subsets of CD4+ Th cells, including Th1, Th2, Th17 and T regulatory cells, each activated by a specific set of cytokines and transcription factors and characterized by the cytokines they secrete and effector functions they perform.” https://www.thermofisher.com/ca/en/home/life-science/cell-analysis/cell-analysis-learning-center/immunology-at-work/t-helper-1-cell-overview.html
TH2 / T Helper 2 Cell Response
“…Th2 cells mediate the activation and maintenance of the humoral, or antibody-mediated, immune response against extracellular parasites, bacteria, allergens, and toxins. Th2 cells mediate these functions by producing various cytokines such as IL-4, IL-5, IL-6, IL-9, IL-13, and IL-17E (IL-25). https://www.thermofisher.com/ca/en/home/life-science/cell-analysis/cell-analysis-learning-center/immunology-at-work/t-helper-2-cell-overview.html
Tregs / Regulatory T cells
Regulatory T cells (Tregs) are a specialized subpopulation of T cells that act to suppress immune response, thereby maintaining homeostasis and self-tolerance. It has been shown that Tregs are able to inhibit T cell proliferation and cytokine production and play a critical role in preventing autoimmunity.
TH17 / Helper 17 Cells
Urticaria
Quantity: 30 Vials
Model : ALC
Note: Ergopathics test kits are not intended to diagnose, prevent, treat or cure any disease, disorder or abnormal physical state. The vials contain ethanol and water and the process used to imprint them with electromagnetic signatures has not been tested or validated by any scientific method and is not approved by any regulatory authority. They are intended for use solely by qualified providers to support wellness and manage stress.
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ALLERGIC CASCADE (ALC)
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